Joe Allen has been ruled out of Wales' Euro 2016 qualifier against Israel with a hamstring injury.
The Liverpool midfielder was suspended for the 3 September trip to Cyprus but will also miss the game with Israel three days later in Cardiff.
Defender Adam Matthews is also out after being injured in Sunderland's 6-3 League Cup win against Exeter.
Real Madrid forward Gareth Bale is included having declared his fitness after a toe injury worry.
"When it initially happened [Bale's injury] you're holding your breath a bit, of course," admitted Wales manager Chris Coleman.
"But the scan and the feedback was positive thankfully so I don't think there's going to be a problem.
Source: BBC Sport - Euro 2016: Joe Allen ruled out of Wales qualifiers
How big a blow is this for Wales?
Can they still qualify without the 2 players>